What causes dementia is a BIG question. My personal progress on the matter is that we’ve found some changes in how the brain makes energy in dementia which is different to how healthy brain does it. these could be toxic/damaging so we need to see how widespread this feature is and if we try to stop it does it slow the development of dementia down.
Overall progress has been very disappointing. One big pharmaceutical company has just closed down a programme.
But the age-specific incidence is falling, which is probably something to do with overall health rather than any specific intervention.
However our population has more and more old people so the burden on patients, carers and the whole country is increasing.
Three predictions: There won’t be a magic bullet in the foreseeable future.There will be some incremental improvements from smart combined use of existing interventions. And we will identify subtypes with specific useful interventions.
Jonathan
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Jonathan commented on :
Overall progress has been very disappointing. One big pharmaceutical company has just closed down a programme.
But the age-specific incidence is falling, which is probably something to do with overall health rather than any specific intervention.
However our population has more and more old people so the burden on patients, carers and the whole country is increasing.
Three predictions: There won’t be a magic bullet in the foreseeable future.There will be some incremental improvements from smart combined use of existing interventions. And we will identify subtypes with specific useful interventions.
Jonathan
selinamackemsley commented on :
how will you improve to find out more